The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood. [provided by RefSeq, Oct 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ATP1A2BA-20-REGO | 20 (40 μL) | 200 μL |
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| ATP1A2BA-20-REGR | 20 (40 μL) | 200 μL |
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| ATP1A2BA-20-ORGR | 20 (40 μL) | 200 μL |
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| ATP1A2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| ATP1A2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| ATP1A2BA-20-GROR | 20 (40 μL) | 200 μL |
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| ATP1A2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| ATP1A2BA-20-AQOR | 20 (40 μL) | 200 μL |
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The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood. [provided by RefSeq, Oct 2008]
Gene Symbol : ATP1A2
Gene Name : ATPase Na+/K+ transporting subunit alpha 2
Chromosome : CHR 1: 160,115,729-160,143,590
Locus : 1q23.2
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