ATP6V1B2 Break Apart FISH Probe

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. [provided by RefSeq, Jul 2008]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
ATP6V1B2BA-20-REGO 20 (40 μL) 200 μL color color Request Pricing
ATP6V1B2BA-20-REGR 20 (40 μL) 200 μL color color Request Pricing
ATP6V1B2BA-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
ATP6V1B2BA-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
ATP6V1B2BA-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
ATP6V1B2BA-20-GROR 20 (40 μL) 200 μL color color Request Pricing
ATP6V1B2BA-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
ATP6V1B2BA-20-AQOR 20 (40 μL) 200 μL color color Request Pricing

Gene Summary

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol : ATP6V1B2

Gene Name : ATPase H+ transporting V1 subunit B2

Chromosome : CHR 8: 201,971,92-202,268,51

Locus : 8p21.3

Alt. Genes : AKAP9

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