This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. [provided by RefSeq, Jul 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
ATP6V1B2BA-20-REGO | 20 (40 μL) | 200 μL | Request Pricing | |
ATP6V1B2BA-20-REGR | 20 (40 μL) | 200 μL | Request Pricing | |
ATP6V1B2BA-20-ORGR | 20 (40 μL) | 200 μL | Request Pricing | |
ATP6V1B2BA-20-GOGR | 20 (40 μL) | 200 μL | Request Pricing | |
ATP6V1B2BA-20-GRRE | 20 (40 μL) | 200 μL | Request Pricing | |
ATP6V1B2BA-20-GROR | 20 (40 μL) | 200 μL | Request Pricing | |
ATP6V1B2BA-20-GRGO | 20 (40 μL) | 200 μL | Request Pricing | |
ATP6V1B2BA-20-AQOR | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. [provided by RefSeq, Jul 2008]
Gene Symbol : ATP6V1B2
Gene Name : ATPase H+ transporting V1 subunit B2
Chromosome : CHR 8: 201,971,92-202,268,51
Locus : 8p21.3
Alt. Genes : AKAP9
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