This gene encodes an adaptor protein that belongs to the bicaudal D family of dynein cargo adaptors. The encoded protein acts as an intracellular cargo transport cofactor that regulates the microtubule-based loading of cargo onto the dynein motor complex. It also controls dynein motor activity and coordination. It has a domain architecture consisting of coiled-coil domains at the N- and C-termini that are highly conserved in other family members. Naturally occurring mutations in this gene are associated with short telomere length and emphysema. [provided by RefSeq, Aug 2017]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
BICD1BA-20-REGO | 20 (40 μL) | 200 μL | Request Pricing | |
BICD1BA-20-REGR | 20 (40 μL) | 200 μL | Request Pricing | |
BICD1BA-20-ORGR | 20 (40 μL) | 200 μL | Request Pricing | |
BICD1BA-20-GOGR | 20 (40 μL) | 200 μL | Request Pricing | |
BICD1BA-20-GRRE | 20 (40 μL) | 200 μL | Request Pricing | |
BICD1BA-20-GROR | 20 (40 μL) | 200 μL | Request Pricing | |
BICD1BA-20-GRGO | 20 (40 μL) | 200 μL | Request Pricing | |
BICD1BA-20-AQOR | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes an adaptor protein that belongs to the bicaudal D family of dynein cargo adaptors. The encoded protein acts as an intracellular cargo transport cofactor that regulates the microtubule-based loading of cargo onto the dynein motor complex. It also controls dynein motor activity and coordination. It has a domain architecture consisting of coiled-coil domains at the N- and C-termini that are highly conserved in other family members. Naturally occurring mutations in this gene are associated with short telomere length and emphysema. [provided by RefSeq, Aug 2017]
Gene Symbol : BICD1
Gene Name : BICD cargo adaptor 1
Chromosome : CHR 12: 321,067,35-323,836,36
Locus : 12p11.21
Alt. Genes : LINC01587
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