The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. [provided by RefSeq, Sep 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BIKBA-20-REGO | 20 (40 μL) | 200 μL |
|
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| BIKBA-20-REGR | 20 (40 μL) | 200 μL |
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| BIKBA-20-ORGR | 20 (40 μL) | 200 μL |
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| BIKBA-20-GOGR | 20 (40 μL) | 200 μL |
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| BIKBA-20-GRRE | 20 (40 μL) | 200 μL |
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| BIKBA-20-GROR | 20 (40 μL) | 200 μL |
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| BIKBA-20-GRGO | 20 (40 μL) | 200 μL |
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| BIKBA-20-AQOR | 20 (40 μL) | 200 μL |
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The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. [provided by RefSeq, Sep 2011]
Gene Symbol : BIK
Gene Name : BCL2 interacting killer
Chromosome : CHR 22: 431,107,47-431,297,11
Locus : 22q13.2
Alt. Genes : AP3S2
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