Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BLMHBA-20-REGO | 20 (40 μL) | 200 μL |
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| BLMHBA-20-REGR | 20 (40 μL) | 200 μL |
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| BLMHBA-20-ORGR | 20 (40 μL) | 200 μL |
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| BLMHBA-20-GOGR | 20 (40 μL) | 200 μL |
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| BLMHBA-20-GRRE | 20 (40 μL) | 200 μL |
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| BLMHBA-20-GROR | 20 (40 μL) | 200 μL |
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| BLMHBA-20-GRGO | 20 (40 μL) | 200 μL |
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| BLMHBA-20-AQOR | 20 (40 μL) | 200 μL |
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Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. [provided by RefSeq, Jul 2008]
Gene Symbol : BLMH
Gene Name : Bleomycin hydrolase
Chromosome : CHR 17: 302,921,65-302,481,94
Locus : 17q11.2
Alt. Genes : ENAM
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