This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BUB1BBA-20-REGO | 20 (40 μL) | 200 μL |
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| BUB1BBA-20-REGR | 20 (40 μL) | 200 μL |
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| BUB1BBA-20-ORGR | 20 (40 μL) | 200 μL |
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| BUB1BBA-20-GOGR | 20 (40 μL) | 200 μL |
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| BUB1BBA-20-GRRE | 20 (40 μL) | 200 μL |
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| BUB1BBA-20-GROR | 20 (40 μL) | 200 μL |
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| BUB1BBA-20-GRGO | 20 (40 μL) | 200 μL |
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| BUB1BBA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008]
Gene Symbol : BUB1B
Gene Name : BUB1 mitotic checkpoint serine/threonine kinase B
Chromosome : CHR 15: 401,610,08-402,211,35
Locus : 15q15.1
Alt. Genes : SGK2
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