This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CAPNS1BA-20-REGO | 20 (40 μL) | 200 μL |
|
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| CAPNS1BA-20-REGR | 20 (40 μL) | 200 μL |
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| CAPNS1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| CAPNS1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| CAPNS1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| CAPNS1BA-20-GROR | 20 (40 μL) | 200 μL |
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| CAPNS1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| CAPNS1BA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Gene Symbol : CAPNS1
Gene Name : Calpain small subunit 1
Chromosome : CHR 19: 361,399,25-361,503,52
Locus : 19q13.12
Alt. Genes : PDZK1IP1
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