This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CASP2BA-20-REGO | 20 (40 μL) | 200 μL |
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| CASP2BA-20-REGR | 20 (40 μL) | 200 μL |
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| CASP2BA-20-ORGR | 20 (40 μL) | 200 μL |
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| CASP2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| CASP2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| CASP2BA-20-GROR | 20 (40 μL) | 200 μL |
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| CASP2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| CASP2BA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Gene Symbol : CASP2
Gene Name : Caspase 2
Chromosome : CHR 7: 143,288,214-143,307,695
Locus : 7q34
Alt. Genes : KIF20A
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