CCR3 Break Apart FISH Probe

The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
CCR3BA-20-REGO 20 (40 μL) 200 μL color color Request Pricing
CCR3BA-20-REGR 20 (40 μL) 200 μL color color Request Pricing
CCR3BA-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
CCR3BA-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
CCR3BA-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
CCR3BA-20-GROR 20 (40 μL) 200 μL color color Request Pricing
CCR3BA-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
CCR3BA-20-AQOR 20 (40 μL) 200 μL color color Request Pricing

Gene Summary

The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]

Gene Details

Gene Symbol : CCR3

Gene Name : C-C motif chemokine receptor 3

Chromosome : CHR 3: 462,106,98-462,667,05

Locus : 3p21.31

Alt. Genes : CHST4

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