The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CCR7BA-20-REGO | 20 (40 μL) | 200 μL |
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| CCR7BA-20-REGR | 20 (40 μL) | 200 μL |
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| CCR7BA-20-ORGR | 20 (40 μL) | 200 μL |
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| CCR7BA-20-GOGR | 20 (40 μL) | 200 μL |
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| CCR7BA-20-GRRE | 20 (40 μL) | 200 μL |
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| CCR7BA-20-GROR | 20 (40 μL) | 200 μL |
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| CCR7BA-20-GRGO | 20 (40 μL) | 200 μL |
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| CCR7BA-20-AQOR | 20 (40 μL) | 200 μL |
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The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Gene Symbol : CCR7
Gene Name : C-C motif chemokine receptor 7
Chromosome : CHR 17: 405,654,83-405,537,68
Locus : 17q21.2
Alt. Genes : ZNF263
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