This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CD86BA-20-REGO | 20 (40 μL) | 200 μL |
|
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| CD86BA-20-REGR | 20 (40 μL) | 200 μL |
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| CD86BA-20-ORGR | 20 (40 μL) | 200 μL |
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| CD86BA-20-GOGR | 20 (40 μL) | 200 μL |
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| CD86BA-20-GRRE | 20 (40 μL) | 200 μL |
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| CD86BA-20-GROR | 20 (40 μL) | 200 μL |
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| CD86BA-20-GRGO | 20 (40 μL) | 200 μL |
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| CD86BA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
Gene Symbol : CD86
Gene Name : CD86 molecule
Chromosome : CHR 3: 122,055,361-122,121,142
Locus : 3q13.33
Alt. Genes : ATP6AP2
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