Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas or fecal material is actually referring to chymotrypsin-like elastase family, member 3B. [provided by RefSeq, May 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CELA1BA-20-REGO | 20 (40 μL) | 200 μL |
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| CELA1BA-20-REGR | 20 (40 μL) | 200 μL |
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| CELA1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| CELA1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| CELA1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| CELA1BA-20-GROR | 20 (40 μL) | 200 μL |
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| CELA1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| CELA1BA-20-AQOR | 20 (40 μL) | 200 μL |
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Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas or fecal material is actually referring to chymotrypsin-like elastase family, member 3B. [provided by RefSeq, May 2009]
Gene Symbol : CELA1
Gene Name : Chymotrypsin like elastase family member 1
Chromosome : CHR 12: 513,466,78-513,284,42
Locus : 12q13.13
Alt. Genes : PLXNC1
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