The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CHD4BA-20-REGO | 20 (40 μL) | 200 μL |
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| CHD4BA-20-REGR | 20 (40 μL) | 200 μL |
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| CHD4BA-20-ORGR | 20 (40 μL) | 200 μL |
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| CHD4BA-20-GOGR | 20 (40 μL) | 200 μL |
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| CHD4BA-20-GRRE | 20 (40 μL) | 200 μL |
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| CHD4BA-20-GROR | 20 (40 μL) | 200 μL |
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| CHD4BA-20-GRGO | 20 (40 μL) | 200 μL |
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| CHD4BA-20-AQOR | 20 (40 μL) | 200 μL |
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The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
Gene Symbol : CHD4
Gene Name : Chromodomain helicase DNA binding protein 4
Chromosome : CHR 12: 660,743,8-657,008,1
Locus : 12p13.31
Alt. Genes : ENAM
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