In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| COPABA-20-REGO | 20 (40 μL) | 200 μL |
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| COPABA-20-REGR | 20 (40 μL) | 200 μL |
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| COPABA-20-ORGR | 20 (40 μL) | 200 μL |
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| COPABA-20-GOGR | 20 (40 μL) | 200 μL |
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| COPABA-20-GRRE | 20 (40 μL) | 200 μL |
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| COPABA-20-GROR | 20 (40 μL) | 200 μL |
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| COPABA-20-GRGO | 20 (40 μL) | 200 μL |
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| COPABA-20-AQOR | 20 (40 μL) | 200 μL |
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In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Gene Symbol : COPA
Gene Name : Coatomer protein complex subunit alpha
Chromosome : CHR 1: 160,343,563-160,288,586
Locus : 1q23.2
Alt. Genes : PREB
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