This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CRY2BA-20-REGO | 20 (40 μL) | 200 μL |
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| CRY2BA-20-REGR | 20 (40 μL) | 200 μL |
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| CRY2BA-20-ORGR | 20 (40 μL) | 200 μL |
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| CRY2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| CRY2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| CRY2BA-20-GROR | 20 (40 μL) | 200 μL |
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| CRY2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| CRY2BA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]
Gene Symbol : CRY2
Gene Name : Cryptochrome circadian regulator 2
Chromosome : CHR 11: 458,471,17-458,832,47
Locus : 11p11.2
Alt. Genes : PREB
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