Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. [provided by RefSeq, Sep 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CRYMBA-20-REGO | 20 (40 μL) | 200 μL |
|
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| CRYMBA-20-REGR | 20 (40 μL) | 200 μL |
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| CRYMBA-20-ORGR | 20 (40 μL) | 200 μL |
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| CRYMBA-20-GOGR | 20 (40 μL) | 200 μL |
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| CRYMBA-20-GRRE | 20 (40 μL) | 200 μL |
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| CRYMBA-20-GROR | 20 (40 μL) | 200 μL |
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| CRYMBA-20-GRGO | 20 (40 μL) | 200 μL |
|
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| CRYMBA-20-AQOR | 20 (40 μL) | 200 μL |
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Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. [provided by RefSeq, Sep 2014]
Gene Symbol : CRYM
Gene Name : Crystallin mu
Chromosome : CHR 16: 213,031,35-212,585,17
Locus : 16p12.2
Alt. Genes : MKRN3-AS1
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