This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CTSDBA-20-REGO | 20 (40 μL) | 200 μL |
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| CTSDBA-20-REGR | 20 (40 μL) | 200 μL |
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| CTSDBA-20-ORGR | 20 (40 μL) | 200 μL |
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| CTSDBA-20-GOGR | 20 (40 μL) | 200 μL |
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| CTSDBA-20-GRRE | 20 (40 μL) | 200 μL |
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| CTSDBA-20-GROR | 20 (40 μL) | 200 μL |
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| CTSDBA-20-GRGO | 20 (40 μL) | 200 μL |
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| CTSDBA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]
Gene Symbol : CTSD
Gene Name : Cathepsin D
Chromosome : CHR 11: 176,399,1-175,275,1
Locus : 11p15.5
Alt. Genes : SUGP2
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