The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. [provided by RefSeq, Apr 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CTSKBA-20-REGO | 20 (40 μL) | 200 μL |
|
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| CTSKBA-20-REGR | 20 (40 μL) | 200 μL |
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| CTSKBA-20-ORGR | 20 (40 μL) | 200 μL |
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| CTSKBA-20-GOGR | 20 (40 μL) | 200 μL |
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| CTSKBA-20-GRRE | 20 (40 μL) | 200 μL |
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| CTSKBA-20-GROR | 20 (40 μL) | 200 μL |
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| CTSKBA-20-GRGO | 20 (40 μL) | 200 μL |
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| CTSKBA-20-AQOR | 20 (40 μL) | 200 μL |
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The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. [provided by RefSeq, Apr 2013]
Gene Symbol : CTSK
Gene Name : Cathepsin K
Chromosome : CHR 1: 150,808,440-150,796,207
Locus : 1q21.3
Alt. Genes : TRIM28
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