Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CYBABA-20-REGO | 20 (40 μL) | 200 μL |
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| CYBABA-20-REGR | 20 (40 μL) | 200 μL |
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| CYBABA-20-ORGR | 20 (40 μL) | 200 μL |
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| CYBABA-20-GOGR | 20 (40 μL) | 200 μL |
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| CYBABA-20-GRRE | 20 (40 μL) | 200 μL |
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| CYBABA-20-GROR | 20 (40 μL) | 200 μL |
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| CYBABA-20-GRGO | 20 (40 μL) | 200 μL |
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| CYBABA-20-AQOR | 20 (40 μL) | 200 μL |
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Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells. [provided by RefSeq, Jul 2008]
Gene Symbol : CYBA
Gene Name : Cytochrome b-245 alpha chain
Chromosome : CHR 16: 886,510,83-886,432,88
Locus : 16q24.2
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