This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CYP11B1BA-20-REGO | 20 (40 μL) | 200 μL |
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| CYP11B1BA-20-REGR | 20 (40 μL) | 200 μL |
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| CYP11B1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| CYP11B1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| CYP11B1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| CYP11B1BA-20-GROR | 20 (40 μL) | 200 μL |
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| CYP11B1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| CYP11B1BA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : CYP11B1
Gene Name : Cytochrome P450 family 11 subfamily B member 1
Chromosome : CHR 8: 142,879,838-142,872,353
Locus : 8q24.3
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