The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. [provided by RefSeq, Jan 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DAB1BA-20-REGO | 20 (40 μL) | 200 μL |
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| DAB1BA-20-REGR | 20 (40 μL) | 200 μL |
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| DAB1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| DAB1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| DAB1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| DAB1BA-20-GROR | 20 (40 μL) | 200 μL |
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| DAB1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| DAB1BA-20-AQOR | 20 (40 μL) | 200 μL |
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The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. [provided by RefSeq, Jan 2017]
Gene Symbol : DAB1
Gene Name : DAB1, reelin adaptor protein
Chromosome : CHR 1: 582,505,38-569,979,05
Locus : 1p32.2
Alt. Genes : ZNF263
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