DAD1 Break Apart FISH Probe

DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes. [provided by RefSeq, Jul 2008]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
DAD1BA-20-REGO 20 (40 μL) 200 μL color color Request Pricing
DAD1BA-20-REGR 20 (40 μL) 200 μL color color Request Pricing
DAD1BA-20-ORGR 20 (40 μL) 200 μL color color Request Pricing
DAD1BA-20-GOGR 20 (40 μL) 200 μL color color Request Pricing
DAD1BA-20-GRRE 20 (40 μL) 200 μL color color Request Pricing
DAD1BA-20-GROR 20 (40 μL) 200 μL color color Request Pricing
DAD1BA-20-GRGO 20 (40 μL) 200 μL color color Request Pricing
DAD1BA-20-AQOR 20 (40 μL) 200 μL color color Request Pricing

Gene Summary

DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol : DAD1

Gene Name : Defender against cell death 1

Chromosome : CHR 14: 225,892,36-225,649,06

Locus : 14q11.2

Alt. Genes : MKRN3-AS1

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