The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DCTDBA-20-REGO | 20 (40 μL) | 200 μL |
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| DCTDBA-20-REGR | 20 (40 μL) | 200 μL |
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| DCTDBA-20-ORGR | 20 (40 μL) | 200 μL |
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| DCTDBA-20-GOGR | 20 (40 μL) | 200 μL |
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| DCTDBA-20-GRRE | 20 (40 μL) | 200 μL |
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| DCTDBA-20-GROR | 20 (40 μL) | 200 μL |
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| DCTDBA-20-GRGO | 20 (40 μL) | 200 μL |
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| DCTDBA-20-AQOR | 20 (40 μL) | 200 μL |
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The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : DCTD
Gene Name : DCMP deaminase
Chromosome : CHR 4: 182,917,476-182,890,090
Locus : 4q35.1
Alt. Genes : FEM1B
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