This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked cognitive disability. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DLG3BA-20-REGO | 20 (40 μL) | 200 μL |
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| DLG3BA-20-REGR | 20 (40 μL) | 200 μL |
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| DLG3BA-20-ORGR | 20 (40 μL) | 200 μL |
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| DLG3BA-20-GOGR | 20 (40 μL) | 200 μL |
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| DLG3BA-20-GRRE | 20 (40 μL) | 200 μL |
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| DLG3BA-20-GROR | 20 (40 μL) | 200 μL |
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| DLG3BA-20-GRGO | 20 (40 μL) | 200 μL |
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| DLG3BA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked cognitive disability. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]
Gene Symbol : DLG3
Gene Name : Discs large MAGUK scaffold protein 3
Chromosome : CHR X: 704,448,49-705,054,89
Locus : Xq13.1
Alt. Genes : OPTN
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