This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DNASE2BA-20-REGO | 20 (40 μL) | 200 μL |
|
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| DNASE2BA-20-REGR | 20 (40 μL) | 200 μL |
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| DNASE2BA-20-ORGR | 20 (40 μL) | 200 μL |
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| DNASE2BA-20-GOGR | 20 (40 μL) | 200 μL |
|
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| DNASE2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| DNASE2BA-20-GROR | 20 (40 μL) | 200 μL |
|
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| DNASE2BA-20-GRGO | 20 (40 μL) | 200 μL |
|
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| DNASE2BA-20-AQOR | 20 (40 μL) | 200 μL |
|
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This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record. [provided by RefSeq, Jul 2008]
Gene Symbol : DNASE2
Gene Name : Deoxyribonuclease 2, lysosomal
Chromosome : CHR 19: 128,815,20-128,752,10
Locus : 19p13.13
Alt. Genes : CLEC3A
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