This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DOCK1BA-20-REGO | 20 (40 μL) | 200 μL |
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| DOCK1BA-20-REGR | 20 (40 μL) | 200 μL |
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| DOCK1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| DOCK1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| DOCK1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| DOCK1BA-20-GROR | 20 (40 μL) | 200 μL |
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| DOCK1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| DOCK1BA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Gene Symbol : DOCK1
Gene Name : Dedicator of cytokinesis 1
Chromosome : CHR 10: 126,905,408-127,452,516
Locus : 10q26.2
Alt. Genes : LINC01587
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