This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DRD2BA-20-REGO | 20 (40 μL) | 200 μL |
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| DRD2BA-20-REGR | 20 (40 μL) | 200 μL |
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| DRD2BA-20-ORGR | 20 (40 μL) | 200 μL |
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| DRD2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| DRD2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| DRD2BA-20-GROR | 20 (40 μL) | 200 μL |
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| DRD2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| DRD2BA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]
Gene Symbol : DRD2
Gene Name : Dopamine receptor D2
Chromosome : CHR 11: 113,475,278-113,409,594
Locus : 11q23.2
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