The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
EIF4EBA-20-REGO | 20 (40 μL) | 200 μL | Request Pricing | |
EIF4EBA-20-REGR | 20 (40 μL) | 200 μL | Request Pricing | |
EIF4EBA-20-ORGR | 20 (40 μL) | 200 μL | Request Pricing | |
EIF4EBA-20-GOGR | 20 (40 μL) | 200 μL | Request Pricing | |
EIF4EBA-20-GRRE | 20 (40 μL) | 200 μL | Request Pricing | |
EIF4EBA-20-GROR | 20 (40 μL) | 200 μL | Request Pricing | |
EIF4EBA-20-GRGO | 20 (40 μL) | 200 μL | Request Pricing | |
EIF4EBA-20-AQOR | 20 (40 μL) | 200 μL | Request Pricing |
The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Gene Symbol : EIF4E
Gene Name : Eukaryotic translation initiation factor 4E
Chromosome : CHR 4: 989,306,34-988,784,55
Locus : 4q23
Alt. Genes : G3BP1
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