This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EYA3BA-20-REGO | 20 (40 μL) | 200 μL |
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| EYA3BA-20-REGR | 20 (40 μL) | 200 μL |
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| EYA3BA-20-ORGR | 20 (40 μL) | 200 μL |
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| EYA3BA-20-GOGR | 20 (40 μL) | 200 μL |
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| EYA3BA-20-GRRE | 20 (40 μL) | 200 μL |
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| EYA3BA-20-GROR | 20 (40 μL) | 200 μL |
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| EYA3BA-20-GRGO | 20 (40 μL) | 200 μL |
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| EYA3BA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Symbol : EYA3
Gene Name : EYA transcriptional coactivator and phosphatase 3
Chromosome : CHR 1: 280,886,70-279,703,43
Locus : 1p35.3
Alt. Genes : HIPK3
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