The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| JAG1BA-20-REGO | 20 (40 μL) | 200 μL |
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| JAG1BA-20-REGR | 20 (40 μL) | 200 μL |
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| JAG1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| JAG1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| JAG1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| JAG1BA-20-GROR | 20 (40 μL) | 200 μL |
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| JAG1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| JAG1BA-20-AQOR | 20 (40 μL) | 200 μL |
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The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008]
Gene Symbol : JAG1
Gene Name : Jagged 1
Chromosome : CHR 20: 106,740,45-106,376,83
Locus : 20p12.2
Alt. Genes : KIF20A
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