The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LRBABA-20-REGO | 20 (40 μL) | 200 μL |
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| LRBABA-20-REGR | 20 (40 μL) | 200 μL |
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| LRBABA-20-ORGR | 20 (40 μL) | 200 μL |
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| LRBABA-20-GOGR | 20 (40 μL) | 200 μL |
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| LRBABA-20-GRRE | 20 (40 μL) | 200 μL |
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| LRBABA-20-GROR | 20 (40 μL) | 200 μL |
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| LRBABA-20-GRGO | 20 (40 μL) | 200 μL |
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| LRBABA-20-AQOR | 20 (40 μL) | 200 μL |
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The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
Gene Symbol : LRBA
Gene Name : LPS responsive beige-like anchor protein
Chromosome : CHR 4: 151,015,724-150,264,514
Locus : 4q31.3
Alt. Genes : ZNF263
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