Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RUNX1BA-20-REGO | 20 (40 μL) | 200 μL |
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| RUNX1BA-20-REGR | 20 (40 μL) | 200 μL |
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| RUNX1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| RUNX1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| RUNX1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| RUNX1BA-20-GROR | 20 (40 μL) | 200 μL |
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| RUNX1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| RUNX1BA-20-AQOR | 20 (40 μL) | 200 μL |
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Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : RUNX1
Gene Name : Runt related transcription factor 1
Chromosome : CHR 21: 350,493,33-347,878,00
Locus : 21q22.12
Alt. Genes : KIF20A
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