This gene encodes an enzyme localized to the mitochondrial matrix which catalyzes the oxidative demethylation of sarcosine. This enzyme is distinct from another mitochondrial matrix enzyme, dimethylglycine dehydrogenase, which catalyzes a reaction resulting in the formation of sarcosine. Mutations in this gene are associated with sarcosinemia. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SARDHBA-20-REGO | 20 (40 μL) | 200 μL |
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| SARDHBA-20-REGR | 20 (40 μL) | 200 μL |
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| SARDHBA-20-ORGR | 20 (40 μL) | 200 μL |
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| SARDHBA-20-GOGR | 20 (40 μL) | 200 μL |
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| SARDHBA-20-GRRE | 20 (40 μL) | 200 μL |
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| SARDHBA-20-GROR | 20 (40 μL) | 200 μL |
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| SARDHBA-20-GRGO | 20 (40 μL) | 200 μL |
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| SARDHBA-20-AQOR | 20 (40 μL) | 200 μL |
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This gene encodes an enzyme localized to the mitochondrial matrix which catalyzes the oxidative demethylation of sarcosine. This enzyme is distinct from another mitochondrial matrix enzyme, dimethylglycine dehydrogenase, which catalyzes a reaction resulting in the formation of sarcosine. Mutations in this gene are associated with sarcosinemia. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2008]
Gene Symbol : SARDH
Gene Name : Sarcosine dehydrogenase
Chromosome : CHR 9: 133,739,957-133,663,073
Locus : 9q34.2
Alt. Genes : DNAL4
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