The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TRIM23BA-20-REGO | 20 (40 μL) | 200 μL |
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| TRIM23BA-20-REGR | 20 (40 μL) | 200 μL |
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| TRIM23BA-20-ORGR | 20 (40 μL) | 200 μL |
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| TRIM23BA-20-GOGR | 20 (40 μL) | 200 μL |
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| TRIM23BA-20-GRRE | 20 (40 μL) | 200 μL |
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| TRIM23BA-20-GROR | 20 (40 μL) | 200 μL |
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| TRIM23BA-20-GRGO | 20 (40 μL) | 200 μL |
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| TRIM23BA-20-AQOR | 20 (40 μL) | 200 μL |
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The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described. [provided by RefSeq, Jul 2008]
Gene Symbol : TRIM23
Gene Name : Tripartite motif containing 23
Chromosome : CHR 5: 656,243,59-655,896,79
Locus : 5q12.3
Alt. Genes : ENAM
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