NOS3 Summary

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016]

NOS3 Details

Gene Symbol : NOS3

Gene Name : Nitric oxide synthase 3

Chromosome : CHR 7: 150,991,055-151,014,598

Locus : 7q36.1

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ABCB8 Summary

This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

ABCB8 Details

Gene Symbol : ABCB8

Gene Name : ATP binding cassette subfamily B member 8

Chromosome : CHR 7: 151,028,421-151,047,781

Locus : 7q36.1

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