| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ACACA-MED1-20-RERE | 20 (40 μL) | 200 μL |
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| ACACA-MED1-20-REOR | 20 (40 μL) | 200 μL |
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| ACACA-MED1-20-REGO | 20 (40 μL) | 200 μL |
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| ACACA-MED1-20-REGR | 20 (40 μL) | 200 μL |
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| ACACA-MED1-20-REAQ | 20 (40 μL) | 200 μL |
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| ACACA-MED1-20-ORRE | 20 (40 μL) | 200 μL |
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| ACACA-MED1-20-OROR | 20 (40 μL) | 200 μL |
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| ACACA-MED1-20-ORGO | 20 (40 μL) | 200 μL |
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| ACACA-MED1-20-ORGR | 20 (40 μL) | 200 μL |
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| ACACA-MED1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACACA-MED1-20-GORE | 20 (40 μL) | 200 μL |
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| ACACA-MED1-20-GOOR | 20 (40 μL) | 200 μL |
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| ACACA-MED1-20-GOGO | 20 (40 μL) | 200 μL |
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| ACACA-MED1-20-GOGR | 20 (40 μL) | 200 μL |
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| ACACA-MED1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACACA-MED1-20-GRRE | 20 (40 μL) | 200 μL |
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| ACACA-MED1-20-GROR | 20 (40 μL) | 200 μL |
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| ACACA-MED1-20-GRGO | 20 (40 μL) | 200 μL |
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| ACACA-MED1-20-GRGR | 20 (40 μL) | 200 μL |
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| ACACA-MED1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACACA-MED1-20-AQRE | 20 (40 μL) | 200 μL |
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| ACACA-MED1-20-AQOR | 20 (40 μL) | 200 μL |
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| ACACA-MED1-20-AQGO | 20 (40 μL) | 200 μL |
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| ACACA-MED1-20-AQGR | 20 (40 μL) | 200 μL |
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| ACACA-MED1-20-AQAQ | 20 (40 μL) | 200 μL |
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Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : ACACA
Gene Name : Acetyl-CoA carboxylase alpha
Chromosome : CHR 17: 374,068,21-370,849,91
Locus : 17q12
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq, Jul 2008]
Gene Symbol : MED1
Gene Name : Mediator complex subunit 1
Chromosome : CHR 17: 394,512,80-394,042,84
Locus : 17q12
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