| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ACO2-ARHGAP8-20-RERE | 20 (40 μL) | 200 μL |
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| ACO2-ARHGAP8-20-REOR | 20 (40 μL) | 200 μL |
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| ACO2-ARHGAP8-20-REGO | 20 (40 μL) | 200 μL |
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| ACO2-ARHGAP8-20-REGR | 20 (40 μL) | 200 μL |
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| ACO2-ARHGAP8-20-REAQ | 20 (40 μL) | 200 μL |
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| ACO2-ARHGAP8-20-ORRE | 20 (40 μL) | 200 μL |
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| ACO2-ARHGAP8-20-OROR | 20 (40 μL) | 200 μL |
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| ACO2-ARHGAP8-20-ORGO | 20 (40 μL) | 200 μL |
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| ACO2-ARHGAP8-20-ORGR | 20 (40 μL) | 200 μL |
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| ACO2-ARHGAP8-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACO2-ARHGAP8-20-GORE | 20 (40 μL) | 200 μL |
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| ACO2-ARHGAP8-20-GOOR | 20 (40 μL) | 200 μL |
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| ACO2-ARHGAP8-20-GOGO | 20 (40 μL) | 200 μL |
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| ACO2-ARHGAP8-20-GOGR | 20 (40 μL) | 200 μL |
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| ACO2-ARHGAP8-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACO2-ARHGAP8-20-GRRE | 20 (40 μL) | 200 μL |
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| ACO2-ARHGAP8-20-GROR | 20 (40 μL) | 200 μL |
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| ACO2-ARHGAP8-20-GRGO | 20 (40 μL) | 200 μL |
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| ACO2-ARHGAP8-20-GRGR | 20 (40 μL) | 200 μL |
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| ACO2-ARHGAP8-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACO2-ARHGAP8-20-AQRE | 20 (40 μL) | 200 μL |
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| ACO2-ARHGAP8-20-AQOR | 20 (40 μL) | 200 μL |
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| ACO2-ARHGAP8-20-AQGO | 20 (40 μL) | 200 μL |
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| ACO2-ARHGAP8-20-AQGR | 20 (40 μL) | 200 μL |
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| ACO2-ARHGAP8-20-AQAQ | 20 (40 μL) | 200 μL |
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The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq, Jul 2008]
Gene Symbol : ACO2
Gene Name : Aconitase 2
Chromosome : CHR 22: 414,691,24-415,289,88
Locus : 22q13.2
This gene encodes a member of the RHOGAP family. GAP (GTPase-activating) family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. GAP proteins alternate between an active (GTP-bound) and inactive (GDP-bound) state based on the GTP:GDP ratio in the cell. This family member is a multidomain protein that functions to promote Erk activation and cell motility. Alternative splicing results in multiple transcript variants. Read-through transcripts from the upstream proline rich 5, renal (PRR5) gene into this gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene. [provided by RefSeq, Nov 2010]
Gene Symbol : ARHGAP8
Gene Name : Rho GTPase activating protein 8
Chromosome : CHR 22: 447,525,57-448,627,83
Locus : 22q13.31
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