| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ACP2-MRPL48-20-RERE | 20 (40 μL) | 200 μL |
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| ACP2-MRPL48-20-REOR | 20 (40 μL) | 200 μL |
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| ACP2-MRPL48-20-REGO | 20 (40 μL) | 200 μL |
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| ACP2-MRPL48-20-REGR | 20 (40 μL) | 200 μL |
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| ACP2-MRPL48-20-REAQ | 20 (40 μL) | 200 μL |
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| ACP2-MRPL48-20-ORRE | 20 (40 μL) | 200 μL |
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| ACP2-MRPL48-20-OROR | 20 (40 μL) | 200 μL |
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| ACP2-MRPL48-20-ORGO | 20 (40 μL) | 200 μL |
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| ACP2-MRPL48-20-ORGR | 20 (40 μL) | 200 μL |
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| ACP2-MRPL48-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACP2-MRPL48-20-GORE | 20 (40 μL) | 200 μL |
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| ACP2-MRPL48-20-GOOR | 20 (40 μL) | 200 μL |
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| ACP2-MRPL48-20-GOGO | 20 (40 μL) | 200 μL |
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| ACP2-MRPL48-20-GOGR | 20 (40 μL) | 200 μL |
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| ACP2-MRPL48-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACP2-MRPL48-20-GRRE | 20 (40 μL) | 200 μL |
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| ACP2-MRPL48-20-GROR | 20 (40 μL) | 200 μL |
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| ACP2-MRPL48-20-GRGO | 20 (40 μL) | 200 μL |
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| ACP2-MRPL48-20-GRGR | 20 (40 μL) | 200 μL |
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| ACP2-MRPL48-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACP2-MRPL48-20-AQRE | 20 (40 μL) | 200 μL |
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| ACP2-MRPL48-20-AQOR | 20 (40 μL) | 200 μL |
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| ACP2-MRPL48-20-AQGO | 20 (40 μL) | 200 μL |
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| ACP2-MRPL48-20-AQGR | 20 (40 μL) | 200 μL |
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| ACP2-MRPL48-20-AQAQ | 20 (40 μL) | 200 μL |
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The protein encoded by this gene belongs to the histidine acid phosphatase family, which hydrolyze orthophosphoric monoesters to alcohol and phosphate. This protein is localized to the lysosomal membrane, and is chemically and genetically distinct from the red cell acid phosphatase. Mice lacking this gene showed multiple defects, including bone structure alterations, lysosomal storage defects, and an increased tendency towards seizures. An enzymatically-inactive allele of this gene in mice showed severe growth retardation, hair-follicle abnormalities, and an ataxia-like phenotype. Alternatively spliced transcript variants have been found for this gene. A C-terminally extended isoform is also predicted to be produced by the use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism. [provided by RefSeq, Oct 2017]
Gene Symbol : ACP2
Gene Name : Acid phosphatase 2, lysosomal
Chromosome : CHR 11: 472,488,46-472,393,01
Locus : 11p12-p11
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene. [provided by RefSeq, Jan 2016]
Gene Symbol : MRPL48
Gene Name : Mitochondrial ribosomal protein L48
Chromosome : CHR 11: 737,878,71-738,646,10
Locus : 11q13.4
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