PIAS3 Summary

This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]

PIAS3 Details

Gene Symbol : PIAS3

Gene Name : Protein inhibitor of activated STAT 3

Chromosome : CHR 1: 145,859,080-145,848,521

Locus : 1q21.1

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ACP6 Summary

This gene encodes a member of the histidine acid phosphatase protein family. The encoded protein hydrolyzes lysophosphatidic acid, which is involved in G protein-coupled receptor signaling, lipid raft modulation, and in balancing lipid composition within the cell. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2016]

ACP6 Details

Gene Symbol : ACP6

Gene Name : Acid phosphatase 6, lysophosphatidic

Chromosome : CHR 1: 147,670,542-147,629,657

Locus : 1q21.2

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