ACPP Summary

This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway. [provided by RefSeq, Sep 2008]

ACPP Details

Gene Symbol : ACPP

Gene Name : Acid phosphatase, prostate

Chromosome : CHR 3: 132,317,366-132,368,764

Locus : 3q22.1

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ATP2C1 Summary

The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium ions. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]

ATP2C1 Details

Gene Symbol : ATP2C1

Gene Name : ATPase secretory pathway Ca2+ transporting 1

Chromosome : CHR 3: 130,850,499-131,016,711

Locus : 3q22.1

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