ACSL3 Summary

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92% identical to that of rat homolog. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

ACSL3 Details

Gene Symbol : ACSL3

Gene Name : Acyl-CoA synthetase long chain family member 3

Chromosome : CHR 2: 222,860,983-222,944,623

Locus : 2q36.1

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MOGAT1 Summary

Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerols, the precursor of physiologically important lipids such as triacylglycerol and phospholipids (Yen et al., 2002 [PubMed 12077311]).[supplied by OMIM, Mar 2008]

MOGAT1 Details

Gene Symbol : MOGAT1

Gene Name : Monoacylglycerol O-acyltransferase 1

Chromosome : CHR 2: 222,671,737-222,709,929

Locus : 2q36.1

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