| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ACTG1-CLCN3-20-RERE | 20 (40 μL) | 200 μL |
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| ACTG1-CLCN3-20-REOR | 20 (40 μL) | 200 μL |
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| ACTG1-CLCN3-20-REGO | 20 (40 μL) | 200 μL |
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| ACTG1-CLCN3-20-REGR | 20 (40 μL) | 200 μL |
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| ACTG1-CLCN3-20-REAQ | 20 (40 μL) | 200 μL |
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| ACTG1-CLCN3-20-ORRE | 20 (40 μL) | 200 μL |
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| ACTG1-CLCN3-20-OROR | 20 (40 μL) | 200 μL |
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| ACTG1-CLCN3-20-ORGO | 20 (40 μL) | 200 μL |
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| ACTG1-CLCN3-20-ORGR | 20 (40 μL) | 200 μL |
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| ACTG1-CLCN3-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACTG1-CLCN3-20-GORE | 20 (40 μL) | 200 μL |
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| ACTG1-CLCN3-20-GOOR | 20 (40 μL) | 200 μL |
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| ACTG1-CLCN3-20-GOGO | 20 (40 μL) | 200 μL |
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| ACTG1-CLCN3-20-GOGR | 20 (40 μL) | 200 μL |
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| ACTG1-CLCN3-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACTG1-CLCN3-20-GRRE | 20 (40 μL) | 200 μL |
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| ACTG1-CLCN3-20-GROR | 20 (40 μL) | 200 μL |
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| ACTG1-CLCN3-20-GRGO | 20 (40 μL) | 200 μL |
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| ACTG1-CLCN3-20-GRGR | 20 (40 μL) | 200 μL |
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| ACTG1-CLCN3-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACTG1-CLCN3-20-AQRE | 20 (40 μL) | 200 μL |
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| ACTG1-CLCN3-20-AQOR | 20 (40 μL) | 200 μL |
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| ACTG1-CLCN3-20-AQGO | 20 (40 μL) | 200 μL |
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| ACTG1-CLCN3-20-AQGR | 20 (40 μL) | 200 μL |
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| ACTG1-CLCN3-20-AQAQ | 20 (40 μL) | 200 μL |
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Actins are highly conserved proteins that are involved in various types of cell motility and in maintenance of the cytoskeleton. Three main groups of actin isoforms have been identified in vertebrate animals: alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. Actin gamma 1, encoded by this gene, is a cytoplasmic actin found in all cell types. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss and also with Baraitser-Winter syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]
Gene Symbol : ACTG1
Gene Name : Actin gamma 1
Chromosome : CHR 17: 815,128,65-815,099,70
Locus : 17q25.3
This gene encodes a member of the voltage-gated chloride channel (ClC) family. The encoded protein is present in all cell types and localized in plasma membranes and in intracellular vesicles. It is a multi-pass membrane protein which contains a ClC domain and two additional C-terminal CBS (cystathionine beta-synthase) domains. The ClC domain catalyzes the selective flow of Cl- ions across cell membranes, and the CBS domain may have a regulatory function. This protein plays a role in both acidification and transmitter loading of GABAergic synaptic vesicles, and in smooth muscle cell activation and neointima formation. This protein is required for lysophosphatidic acid (LPA)-activated Cl- current activity and fibroblast-to-myofibroblast differentiation. The protein activity is regulated by Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) in glioma cells. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Gene Symbol : CLCN3
Gene Name : Chloride voltage-gated channel 3
Chromosome : CHR 4: 169,620,520-169,723,186
Locus : 4q33
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