| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ACTG1-STAT6-20-RERE | 20 (40 μL) | 200 μL |
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| ACTG1-STAT6-20-REOR | 20 (40 μL) | 200 μL |
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| ACTG1-STAT6-20-REGO | 20 (40 μL) | 200 μL |
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| ACTG1-STAT6-20-REGR | 20 (40 μL) | 200 μL |
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| ACTG1-STAT6-20-REAQ | 20 (40 μL) | 200 μL |
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| ACTG1-STAT6-20-ORRE | 20 (40 μL) | 200 μL |
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| ACTG1-STAT6-20-OROR | 20 (40 μL) | 200 μL |
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| ACTG1-STAT6-20-ORGO | 20 (40 μL) | 200 μL |
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| ACTG1-STAT6-20-ORGR | 20 (40 μL) | 200 μL |
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| ACTG1-STAT6-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACTG1-STAT6-20-GORE | 20 (40 μL) | 200 μL |
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| ACTG1-STAT6-20-GOOR | 20 (40 μL) | 200 μL |
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| ACTG1-STAT6-20-GOGO | 20 (40 μL) | 200 μL |
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| ACTG1-STAT6-20-GOGR | 20 (40 μL) | 200 μL |
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| ACTG1-STAT6-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACTG1-STAT6-20-GRRE | 20 (40 μL) | 200 μL |
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| ACTG1-STAT6-20-GROR | 20 (40 μL) | 200 μL |
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| ACTG1-STAT6-20-GRGO | 20 (40 μL) | 200 μL |
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| ACTG1-STAT6-20-GRGR | 20 (40 μL) | 200 μL |
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| ACTG1-STAT6-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACTG1-STAT6-20-AQRE | 20 (40 μL) | 200 μL |
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| ACTG1-STAT6-20-AQOR | 20 (40 μL) | 200 μL |
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| ACTG1-STAT6-20-AQGO | 20 (40 μL) | 200 μL |
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| ACTG1-STAT6-20-AQGR | 20 (40 μL) | 200 μL |
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| ACTG1-STAT6-20-AQAQ | 20 (40 μL) | 200 μL |
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Actins are highly conserved proteins that are involved in various types of cell motility and in maintenance of the cytoskeleton. Three main groups of actin isoforms have been identified in vertebrate animals: alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. Actin gamma 1, encoded by this gene, is a cytoplasmic actin found in all cell types. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss and also with Baraitser-Winter syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]
Gene Symbol : ACTG1
Gene Name : Actin gamma 1
Chromosome : CHR 17: 815,128,65-815,099,70
Locus : 17q25.3
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Gene Symbol : STAT6
Gene Name : Signal transducer and activator of transcription 6
Chromosome : CHR 12: 571,114,32-570,954,03
Locus : 12q13.3
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