| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ACTN4-YIF1B-20-RERE | 20 (40 μL) | 200 μL |
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| ACTN4-YIF1B-20-REOR | 20 (40 μL) | 200 μL |
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| ACTN4-YIF1B-20-REGO | 20 (40 μL) | 200 μL |
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| ACTN4-YIF1B-20-REGR | 20 (40 μL) | 200 μL |
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| ACTN4-YIF1B-20-REAQ | 20 (40 μL) | 200 μL |
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| ACTN4-YIF1B-20-ORRE | 20 (40 μL) | 200 μL |
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| ACTN4-YIF1B-20-OROR | 20 (40 μL) | 200 μL |
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| ACTN4-YIF1B-20-ORGO | 20 (40 μL) | 200 μL |
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| ACTN4-YIF1B-20-ORGR | 20 (40 μL) | 200 μL |
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| ACTN4-YIF1B-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACTN4-YIF1B-20-GORE | 20 (40 μL) | 200 μL |
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| ACTN4-YIF1B-20-GOOR | 20 (40 μL) | 200 μL |
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| ACTN4-YIF1B-20-GOGO | 20 (40 μL) | 200 μL |
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| ACTN4-YIF1B-20-GOGR | 20 (40 μL) | 200 μL |
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| ACTN4-YIF1B-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACTN4-YIF1B-20-GRRE | 20 (40 μL) | 200 μL |
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| ACTN4-YIF1B-20-GROR | 20 (40 μL) | 200 μL |
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| ACTN4-YIF1B-20-GRGO | 20 (40 μL) | 200 μL |
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| ACTN4-YIF1B-20-GRGR | 20 (40 μL) | 200 μL |
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| ACTN4-YIF1B-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACTN4-YIF1B-20-AQRE | 20 (40 μL) | 200 μL |
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| ACTN4-YIF1B-20-AQOR | 20 (40 μL) | 200 μL |
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| ACTN4-YIF1B-20-AQGO | 20 (40 μL) | 200 μL |
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| ACTN4-YIF1B-20-AQGR | 20 (40 μL) | 200 μL |
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| ACTN4-YIF1B-20-AQAQ | 20 (40 μL) | 200 μL |
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Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq, Jul 2008]
Gene Symbol : ACTN4
Gene Name : Actinin alpha 4
Chromosome : CHR 19: 386,476,15-387,305,31
Locus : 19q13.2
Gene Symbol : YIF1B
Gene Name : Yip1 interacting factor homolog B, membrane trafficking protein
Chromosome : CHR 19: 383,159,75-383,035,59
Locus : 19q13.2
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