| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ACVR2A-KANK1-20-RERE | 20 (40 μL) | 200 μL |
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| ACVR2A-KANK1-20-REOR | 20 (40 μL) | 200 μL |
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| ACVR2A-KANK1-20-REGO | 20 (40 μL) | 200 μL |
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| ACVR2A-KANK1-20-REGR | 20 (40 μL) | 200 μL |
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| ACVR2A-KANK1-20-REAQ | 20 (40 μL) | 200 μL |
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| ACVR2A-KANK1-20-ORRE | 20 (40 μL) | 200 μL |
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| ACVR2A-KANK1-20-OROR | 20 (40 μL) | 200 μL |
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| ACVR2A-KANK1-20-ORGO | 20 (40 μL) | 200 μL |
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| ACVR2A-KANK1-20-ORGR | 20 (40 μL) | 200 μL |
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| ACVR2A-KANK1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACVR2A-KANK1-20-GORE | 20 (40 μL) | 200 μL |
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| ACVR2A-KANK1-20-GOOR | 20 (40 μL) | 200 μL |
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| ACVR2A-KANK1-20-GOGO | 20 (40 μL) | 200 μL |
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| ACVR2A-KANK1-20-GOGR | 20 (40 μL) | 200 μL |
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| ACVR2A-KANK1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACVR2A-KANK1-20-GRRE | 20 (40 μL) | 200 μL |
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| ACVR2A-KANK1-20-GROR | 20 (40 μL) | 200 μL |
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| ACVR2A-KANK1-20-GRGO | 20 (40 μL) | 200 μL |
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| ACVR2A-KANK1-20-GRGR | 20 (40 μL) | 200 μL |
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| ACVR2A-KANK1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACVR2A-KANK1-20-AQRE | 20 (40 μL) | 200 μL |
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| ACVR2A-KANK1-20-AQOR | 20 (40 μL) | 200 μL |
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| ACVR2A-KANK1-20-AQGO | 20 (40 μL) | 200 μL |
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| ACVR2A-KANK1-20-AQGR | 20 (40 μL) | 200 μL |
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| ACVR2A-KANK1-20-AQAQ | 20 (40 μL) | 200 μL |
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This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jun 2013]
Gene Symbol : ACVR2A
Gene Name : Activin A receptor type 2A
Chromosome : CHR 2: 147,844,516-147,930,826
Locus : 2q22.3-q23.1
The protein encoded by this gene belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder. A t(5;9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2014]
Gene Symbol : KANK1
Gene Name : KN motif and ankyrin repeat domains 1
Chromosome : CHR 9: 470,293-746,105
Locus : 9p24.3
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