| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ACVR2A-SUMO1-20-RERE | 20 (40 μL) | 200 μL |
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| ACVR2A-SUMO1-20-REOR | 20 (40 μL) | 200 μL |
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| ACVR2A-SUMO1-20-REGO | 20 (40 μL) | 200 μL |
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| ACVR2A-SUMO1-20-REGR | 20 (40 μL) | 200 μL |
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| ACVR2A-SUMO1-20-REAQ | 20 (40 μL) | 200 μL |
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| ACVR2A-SUMO1-20-ORRE | 20 (40 μL) | 200 μL |
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| ACVR2A-SUMO1-20-OROR | 20 (40 μL) | 200 μL |
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| ACVR2A-SUMO1-20-ORGO | 20 (40 μL) | 200 μL |
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| ACVR2A-SUMO1-20-ORGR | 20 (40 μL) | 200 μL |
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| ACVR2A-SUMO1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACVR2A-SUMO1-20-GORE | 20 (40 μL) | 200 μL |
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| ACVR2A-SUMO1-20-GOOR | 20 (40 μL) | 200 μL |
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| ACVR2A-SUMO1-20-GOGO | 20 (40 μL) | 200 μL |
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| ACVR2A-SUMO1-20-GOGR | 20 (40 μL) | 200 μL |
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| ACVR2A-SUMO1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACVR2A-SUMO1-20-GRRE | 20 (40 μL) | 200 μL |
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| ACVR2A-SUMO1-20-GROR | 20 (40 μL) | 200 μL |
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| ACVR2A-SUMO1-20-GRGO | 20 (40 μL) | 200 μL |
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| ACVR2A-SUMO1-20-GRGR | 20 (40 μL) | 200 μL |
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| ACVR2A-SUMO1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACVR2A-SUMO1-20-AQRE | 20 (40 μL) | 200 μL |
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| ACVR2A-SUMO1-20-AQOR | 20 (40 μL) | 200 μL |
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| ACVR2A-SUMO1-20-AQGO | 20 (40 μL) | 200 μL |
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| ACVR2A-SUMO1-20-AQGR | 20 (40 μL) | 200 μL |
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| ACVR2A-SUMO1-20-AQAQ | 20 (40 μL) | 200 μL |
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This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jun 2013]
Gene Symbol : ACVR2A
Gene Name : Activin A receptor type 2A
Chromosome : CHR 2: 147,844,516-147,930,826
Locus : 2q22.3-q23.1
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]
Gene Symbol : SUMO1
Gene Name : Small ubiquitin-like modifier 1
Chromosome : CHR 2: 202,238,598-202,206,179
Locus : 2q33.1
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