| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ADAMTS16-TERT-20-RERE | 20 (40 μL) | 200 μL |
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| ADAMTS16-TERT-20-REOR | 20 (40 μL) | 200 μL |
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| ADAMTS16-TERT-20-REGO | 20 (40 μL) | 200 μL |
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| ADAMTS16-TERT-20-REGR | 20 (40 μL) | 200 μL |
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| ADAMTS16-TERT-20-REAQ | 20 (40 μL) | 200 μL |
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| ADAMTS16-TERT-20-ORRE | 20 (40 μL) | 200 μL |
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| ADAMTS16-TERT-20-OROR | 20 (40 μL) | 200 μL |
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| ADAMTS16-TERT-20-ORGO | 20 (40 μL) | 200 μL |
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| ADAMTS16-TERT-20-ORGR | 20 (40 μL) | 200 μL |
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| ADAMTS16-TERT-20-ORAQ | 20 (40 μL) | 200 μL |
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| ADAMTS16-TERT-20-GORE | 20 (40 μL) | 200 μL |
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| ADAMTS16-TERT-20-GOOR | 20 (40 μL) | 200 μL |
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| ADAMTS16-TERT-20-GOGO | 20 (40 μL) | 200 μL |
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| ADAMTS16-TERT-20-GOGR | 20 (40 μL) | 200 μL |
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| ADAMTS16-TERT-20-GOAQ | 20 (40 μL) | 200 μL |
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| ADAMTS16-TERT-20-GRRE | 20 (40 μL) | 200 μL |
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| ADAMTS16-TERT-20-GROR | 20 (40 μL) | 200 μL |
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| ADAMTS16-TERT-20-GRGO | 20 (40 μL) | 200 μL |
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| ADAMTS16-TERT-20-GRGR | 20 (40 μL) | 200 μL |
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| ADAMTS16-TERT-20-GRAQ | 20 (40 μL) | 200 μL |
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| ADAMTS16-TERT-20-AQRE | 20 (40 μL) | 200 μL |
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| ADAMTS16-TERT-20-AQOR | 20 (40 μL) | 200 μL |
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| ADAMTS16-TERT-20-AQGO | 20 (40 μL) | 200 μL |
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| ADAMTS16-TERT-20-AQGR | 20 (40 μL) | 200 μL |
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| ADAMTS16-TERT-20-AQAQ | 20 (40 μL) | 200 μL |
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Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity. [provided by RefSeq, Jul 2008]
Gene Symbol : TERT
Gene Name : Telomerase reverse transcriptase
Chromosome : CHR 5: 129,562,5-125,316,6
Locus : 5p15.33
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may inhibit chondrosarcoma cell proliferation and migration. This gene may regulate blood pressure. [provided by RefSeq, May 2016]
Gene Symbol : ADAMTS16
Gene Name : ADAM metallopeptidase with thrombospondin type 1 motif 16
Chromosome : CHR 5: 514,032,9-532,030,3
Locus : 5p15.32
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