ADIPOR1 Summary

This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2014]

ADIPOR1 Details

Gene Symbol : ADIPOR1

Gene Name : Adiponectin receptor 1

Chromosome : CHR 1: 202,958,571-202,940,824

Locus : 1q32.1

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RGS8 Summary

This gene is a member of the regulator of G protein signaling (RGS) family and encodes a protein with a single RGS domain. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. They accelerate transit through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but paradoxically, also accelerate receptor-stimulated activation. [provided by RefSeq, Jul 2008]

RGS8 Details

Gene Symbol : RGS8

Gene Name : Regulator of G protein signaling 8

Chromosome : CHR 1: 182,753,290-182,641,813

Locus : 1q25.3

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