| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AGAP2-PGC-20-RERE | 20 (40 μL) | 200 μL |
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| AGAP2-PGC-20-REOR | 20 (40 μL) | 200 μL |
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| AGAP2-PGC-20-REGO | 20 (40 μL) | 200 μL |
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| AGAP2-PGC-20-REGR | 20 (40 μL) | 200 μL |
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| AGAP2-PGC-20-REAQ | 20 (40 μL) | 200 μL |
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| AGAP2-PGC-20-ORRE | 20 (40 μL) | 200 μL |
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| AGAP2-PGC-20-OROR | 20 (40 μL) | 200 μL |
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| AGAP2-PGC-20-ORGO | 20 (40 μL) | 200 μL |
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| AGAP2-PGC-20-ORGR | 20 (40 μL) | 200 μL |
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| AGAP2-PGC-20-ORAQ | 20 (40 μL) | 200 μL |
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| AGAP2-PGC-20-GORE | 20 (40 μL) | 200 μL |
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| AGAP2-PGC-20-GOOR | 20 (40 μL) | 200 μL |
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| AGAP2-PGC-20-GOGO | 20 (40 μL) | 200 μL |
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| AGAP2-PGC-20-GOGR | 20 (40 μL) | 200 μL |
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| AGAP2-PGC-20-GOAQ | 20 (40 μL) | 200 μL |
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| AGAP2-PGC-20-GRRE | 20 (40 μL) | 200 μL |
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| AGAP2-PGC-20-GROR | 20 (40 μL) | 200 μL |
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| AGAP2-PGC-20-GRGO | 20 (40 μL) | 200 μL |
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| AGAP2-PGC-20-GRGR | 20 (40 μL) | 200 μL |
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| AGAP2-PGC-20-GRAQ | 20 (40 μL) | 200 μL |
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| AGAP2-PGC-20-AQRE | 20 (40 μL) | 200 μL |
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| AGAP2-PGC-20-AQOR | 20 (40 μL) | 200 μL |
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| AGAP2-PGC-20-AQGO | 20 (40 μL) | 200 μL |
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| AGAP2-PGC-20-AQGR | 20 (40 μL) | 200 μL |
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| AGAP2-PGC-20-AQAQ | 20 (40 μL) | 200 μL |
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This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]
Gene Symbol : PGC
Gene Name : Progastricsin
Chromosome : CHR 6: 417,474,00-417,367,10
Locus : 6p21.1
The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Gene Symbol : AGAP2
Gene Name : ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
Chromosome : CHR 12: 577,422,00-577,237,64
Locus : 12q14.1
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