CCL3 Summary

This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.[provided by RefSeq, Sep 2010]

CCL3 Details

Gene Symbol : CCL3

Gene Name : C-C motif chemokine ligand 3

Chromosome : CHR 17: 360,901,59-360,882,55

Locus : 17q12

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AKAP10 Summary

This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins bind to the regulatory subunits of protein kinase A (PKA) and confine the holoenzyme to discrete locations within the cell. The encoded protein is localized to mitochondria and interacts with both the type I and type II regulatory subunits of PKA. Polymorphisms in this gene may be associated with increased risk of arrhythmias and sudden cardiac death. [provided by RefSeq, May 2012]

AKAP10 Details

Gene Symbol : AKAP10

Gene Name : A-kinase anchoring protein 10

Chromosome : CHR 17: 199,778,55-199,044,51

Locus : 17p11.2

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